Rajabally YA, Nicolas G, Pieret F, are the doctors who study the distal acquired demyelinating symmetric polyneuropathy disease in the Columbia University department of neurology. Publication of this research was accepted in January 2012. A 58-year-old woman was diagnosed with the disease. The research concerning this disease was conducted through a survey methodology: the questionnaire method was used. Patients were evaluated in the neurology department at the sapetrie hospital in January 2005-2009. MRI diagnosis was made to obtain the results where it showed no significant humiliation and no treatment was initiated.
Katz JS, Saperstein and Echaniz-Laguna A are the senior medical experts who conducted the research concerning the sensory chronic inflammatory demyelnating polyneurpathy disease (Echaniz Laguna & Philippi, 2009). Questionnaire was used by the experts in conducting the research among the identified patients affected by the disease. The neurology department conducted this research in the year 2005 fulfilling the presence of sensory polyneuropathy allowing the clinical progression of the disease. Questionnaire method of data collection concluded that there was negligence regarding many who have suffered the disease. Questionnaire method was performed as per the current state legislation concerning the research to avoid anonymous data. Neurological examination was conducted in all patients to allow clear results to be obtained through the questionnaire data collection. In order to conduct a research and make a proper conclusion about the desease 22 patients were questioned: 16 were men and 6 women. Research of both diseases is aimed at understanding the disorders and finding ways to prevent them.
Distal acquired demyelinating symmetric polyneuropathy is a disease that is majorly characterized by proximal and distal weaknesses. Patients affected by this kind of disease have sensory numbness and areflexia as a result of predominantly sensory involvement. Experts have proposed that DADS to this disease may end up being the CIDP (Echaniz Laguna & Philippi, 2009). Symptoms of distal acquired disease are intermittent that would gradually become constant affecting human hands. Chronic sensory polyneuropathy experts’ report indicated pathogenic features. Chronic inflammatory demyelinating polyneuropathy is a condition that is characterized by weakness in the legs. This disease is normally caused by myelin sheath damage of nerves, while Distal disease has been classified by the medical experts to have primarily demyelinating basing on the outcome of pathological criteria. The distinction of this distal disease from sensory is due to the fact that neuropathies is amenable to treatment. Sensory chronic inflammatory, on the other hand, is slowly progressive: it normally begins with human feet and latter spreads to hands and legs. Distal disease responds to different therapies if no other cause is not associated. Laboratory studies indicated that a patient affected by overlapping presentation is difficult to diagnose, while Sensory disease slowly progresses for about two months.
Chronic inflammatory disease affects all stages of human life and is common in young people. Symptoms include numbness and weakness in arms, while the patients affected by distal disease experience some pains in lower and upper extremities, which is more likely to affect sensory system and balance sensation leading to inability to walk. Sensory disease does not affect bladder as the distal disease.
Suppressant drugs are used during the treatment of chronic inflammatory disease to improve muscle strength and distortion of the joints in the affected individual (Katz et al. 2000). The causes of chronic inflammatory disease vary from spontaneous recovery to having partial recovery. Chronic inflammatory disease is curable if early treatment is initiated. Research conducted by medical experts through questionnaires under selected patients in the field obtain chronicle involvement of 32% and sensory nerve effects of 59% concluding that all patients are majorly affected by the sensory inflammatory disease. Distal acquired demyelinating symmetric polyneuropathy research experts are concerned that 22% of patients having M-protein are affected by the disease, and there is no possibility to distinguish patients without the disease. The results from the selected sample indicated poor response to immunomodulating therapies. Medical experts found that dental reflexes were absent with no neurological signs indicating spinal root involvement. Prominent swelling in patients and immunoglobin therapy was found to be effective under subsequent recurrences. Patients showed a significant discrepancy in the striking spinal root lesion. Proximal limbs, muscles and impairment along with the nerves cause distal dominance depending on the nerve length (Rajabally et al. 2009).
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The similarities of these diseases are based on the presentation and nerve findings that are consistent. Both have implications of having potential adverse effects of long-term treatment. Drug administering in both the diseases is the same since they portray the same symptoms. Experts have recommended the use of spinal fluids in both diseases as a way of obtaining findings to deal with the condition. Under the same condition, nerve biopsy has been performed by medical experts as a way of reducing myelinated fibers. There is no inflammation in both the sensory and dental diseases (Saperstein et al. 2001). The clinical picture of progressive numbness is one of the similarities of both sensory and dental diseases. Electro diagnostic findings are the most considered diagnostic ways, showing the segmental amplitude changes.
Suppressants are available for these diseases only under doctor’s presentation. Further research is continuously done by medical experts to provide the underlying mechanism of nerve damages that may contribute to effective treatment. Clinical trials have been recognized with the clinical definition based on clinical feature. Define clinical analysis has indicated types of acquired dental and sensory polyneuropathies causes that differ from classic inflammatory. Both have got a response to clinical treatment when it is not clear whether the conditions are variations of chronic inflammatory. Clinical experts suggest that there are a number of patients affected, and they do not satisfy the criteria of diagnosis and still respond to effective treatment.