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Free Essay Sample «Comparison»



Rajabally YA, Nicolas G, Pieret F,  are  the  doctors  who  study  the  distal  acquired  demyelinating  symmetric   polyneuropathy  disease  in  the Columbia University department  of  neurology. Publication of this research was accepted in    January 2012. A  58-year-old woman was diagnosed with the disease. The  research   concerning  this  disease  was  conducted  through  a  survey  methodology: the  questionnaire  method was used. Patients  were  evaluated  in  the  neurology  department  at  the  sapetrie  hospital  in  January  2005-2009. MRI  diagnosis   was  made  to  obtain  the  results    where  it  showed  no  significant  humiliation  and  no  treatment  was  initiated.

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Katz JS, Saperstein and Echaniz-Laguna A  are  the  senior  medical  experts  who  conducted  the  research   concerning  the  sensory  chronic  inflammatory  demyelnating   polyneurpathy  disease (Echaniz Laguna & Philippi, 2009). Questionnaire  was  used  by  the  experts  in  conducting  the  research  among  the  identified  patients  affected  by  the  disease. The  neurology  department  conducted  this  research  in  the  year  2005  fulfilling  the  presence  of  sensory  polyneuropathy  allowing  the clinical progression  of  the  disease. Questionnaire  method  of   data  collection  concluded  that  there was   negligence   regarding  many  who  have  suffered  the  disease. Questionnaire  method  was  performed  as  per  the  current  state  legislation   concerning  the  research  to avoid  anonymous  data. Neurological  examination    was   conducted  in  all  patients  to  allow  clear  results   to  be  obtained  through  the questionnaire data collection. In order to conduct a research  and make a proper conclusion about the desease 22  patients  were questioned:  16  were  men  and  6  women. Research  of  both diseases  is  aimed  at   understanding  the  disorders  and  finding  ways  to  prevent them.


Distal acquired demyelinating symmetric  polyneuropathy    is  a  disease  that  is  majorly  characterized  by  proximal  and  distal  weaknesses. Patients  affected  by  this  kind  of  disease  have  sensory  numbness  and  areflexia  as  a  result  of  predominantly  sensory  involvement. Experts  have  proposed  that    DADS to  this  disease  may  end  up  being  the  CIDP  (Echaniz Laguna & Philippi, 2009). Symptoms    of  distal  acquired  disease  are  intermittent  that  would  gradually   become  constant  affecting  human  hands.  Chronic sensory polyneuropathy   experts’ report indicated pathogenic features. Chronic inflammatory demyelinating polyneuropathy  is  a  condition  that  is  characterized  by  weakness  in  the legs. This  disease  is  normally  caused  by  myelin  sheath  damage  of  nerves,  while Distal  disease  has  been  classified  by  the  medical  experts  to have  primarily  demyelinating  basing  on  the  outcome  of  pathological  criteria. The  distinction  of  this  distal  disease  from  sensory  is  due  to  the  fact  that  neuropathies  is  amenable  to  treatment. Sensory  chronic  inflammatory,  on the  other  hand,  is  slowly  progressive: it  normally  begins  with  human  feet  and  latter  spreads  to  hands  and  legs. Distal  disease  responds  to  different  therapies  if  no  other  cause  is  not  associated. Laboratory  studies  indicated  that  a patient  affected  by  overlapping  presentation  is  difficult  to diagnose, while Sensory  disease  slowly  progresses  for  about  two  months.

Chronic  inflammatory  disease  affects  all  stages of  human  life  and  is  common  in  young  people. Symptoms include numbness and weakness in arms,  while the patients  affected  by  distal  disease  experience  some  pains  in  lower  and  upper  extremities,  which  is  more  likely  to  affect  sensory  system  and  balance  sensation  leading  to  inability  to  walk. Sensory  disease  does not  affect   bladder  as  the distal  disease.

Suppressant drugs  are used  during  the  treatment  of  chronic  inflammatory  disease  to  improve  muscle  strength  and  distortion  of  the joints  in  the  affected   individual (Katz  et al. 2000). The causes  of  chronic  inflammatory disease vary  from spontaneous  recovery  to  having  partial  recovery. Chronic inflammatory   disease is curable if early treatment is   initiated. Research  conducted  by  medical  experts    through  questionnaires  under  selected  patients  in  the  field  obtain  chronicle  involvement    of  32%  and  sensory  nerve  effects  of  59%  concluding  that  all  patients  are  majorly  affected  by  the sensory inflammatory disease. Distal acquired demyelinating symmetric  polyneuropathy    research  experts are   concerned that  22%  of patients  having   M-protein are affected by the disease, and there is  no  possibility  to  distinguish  patients  without  the  disease. The results from the selected   sample indicated poor response   to immunomodulating therapies. Medical experts  found  that  dental  reflexes   were  absent  with  no  neurological  signs  indicating  spinal  root  involvement. Prominent  swelling  in  patients  and  immunoglobin  therapy  was  found   to  be  effective  under  subsequent  recurrences. Patients showed a significant discrepancy in the striking spinal root lesion. Proximal  limbs, muscles  and  impairment  along   with  the  nerves cause  distal  dominance  depending  on  the  nerve  length (Rajabally et al. 2009).

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The similarities of these diseases   are based on the presentation and nerve findings that are consistent. Both have implications of having potential adverse effects of long-term treatment. Drug  administering  in  both  the  diseases  is  the  same  since  they  portray  the  same  symptoms. Experts  have  recommended   the  use  of  spinal  fluids  in  both  diseases  as  a  way  of  obtaining  findings  to  deal  with  the  condition. Under  the  same  condition, nerve  biopsy   has  been  performed  by  medical  experts  as  a  way  of  reducing  myelinated  fibers. There  is  no  inflammation  in  both  the  sensory  and  dental  diseases (Saperstein et  al. 2001). The clinical picture  of  progressive  numbness  is   one  of  the  similarities of  both  sensory  and  dental  diseases. Electro diagnostic  findings  are  the  most  considered  diagnostic  ways, showing  the  segmental  amplitude  changes.

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Suppressants are   available for these diseases only under doctor’s presentation. Further  research  is  continuously   done  by  medical  experts  to  provide  the  underlying  mechanism  of  nerve  damages  that  may  contribute  to  effective  treatment. Clinical trials have been recognized with the clinical definition   based   on clinical feature. Define  clinical  analysis   has  indicated  types  of  acquired  dental  and  sensory  polyneuropathies    causes  that  differ  from  classic  inflammatory. Both  have got  a response  to  clinical  treatment  when it is  not  clear  whether  the  conditions  are  variations  of  chronic  inflammatory. Clinical  experts  suggest  that  there  are  a  number  of  patients  affected, and  they  do  not  satisfy  the  criteria  of  diagnosis  and  still  respond  to  effective  treatment.


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